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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
16.97
Human Site:
S435
Identified Species:
37.33
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
S435
S
L
K
A
E
L
T
S
Q
E
S
Q
I
S
T
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
S435
S
L
K
A
E
L
T
S
Q
E
S
Q
I
S
T
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
K563
E
M
D
Q
Q
K
A
K
L
R
D
M
L
S
D
Dog
Lupus familis
XP_532580
889
97932
S422
S
L
K
A
E
L
T
S
Q
E
S
Q
I
S
T
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
S435
S
L
K
A
E
I
T
S
Q
E
S
Q
I
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
E457
D
I
R
Q
K
C
A
E
E
A
H
L
I
A
M
Frog
Xenopus laevis
O42287
1270
143652
V468
R
E
Q
E
D
I
V
V
L
K
A
K
K
K
T
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
E468
S
L
Q
V
Q
H
S
E
Q
E
Q
R
I
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
E474
K
L
R
Q
Q
A
E
E
Q
E
S
V
L
R
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
S584
S
L
R
G
Q
I
S
S
Q
Q
S
N
V
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
E706
E
L
T
T
D
L
Q
E
S
Q
T
K
N
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
6.6
100
N.A.
86.6
N.A.
N.A.
N.A.
6.6
6.6
40
N.A.
N.A.
33.3
N.A.
33.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
N.A.
N.A.
N.A.
40
46.6
66.6
N.A.
N.A.
53.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
37
0
10
19
0
0
10
10
0
0
19
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
19
0
0
0
0
0
10
0
0
0
19
% D
% Glu:
19
10
0
10
37
0
10
37
10
55
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
0
0
28
0
0
0
0
0
0
55
0
0
% I
% Lys:
10
0
37
0
10
10
0
10
0
10
0
19
10
19
0
% K
% Leu:
0
73
0
0
0
37
0
0
19
0
0
10
19
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
19
28
37
0
10
0
64
19
10
37
0
0
0
% Q
% Arg:
10
0
28
0
0
0
0
0
0
10
0
10
0
10
0
% R
% Ser:
55
0
0
0
0
0
19
46
10
0
55
0
0
55
10
% S
% Thr:
0
0
10
10
0
0
37
0
0
0
10
0
0
0
46
% T
% Val:
0
0
0
10
0
0
10
10
0
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _